Detalhe da pesquisa
1.
Phosphodiesterase in heart and vessels: from physiology to diseases.
Physiol Rev
; 104(2): 765-834, 2024 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37971403
2.
Trial of a Preferential Phosphodiesterase 4B Inhibitor for Idiopathic Pulmonary Fibrosis.
N Engl J Med
; 386(23): 2178-2187, 2022 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-35569036
3.
Systematic review and meta-analysis of the efficacy of olprinone and MEFV gene in treating heart failure.
Cell Mol Biol (Noisy-le-grand)
; 69(3): 82-91, 2023 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37300686
4.
Rolipram and pentoxifylline combination ameliorates the morphological abnormalities of dorsal root ganglion neurons in experimental diabetic neuropathy by reducing mitochondrial dysfunction and apoptosis.
J Biochem Mol Toxicol
; 37(11): e23459, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37431890
5.
Ziritaxestat, a Novel Autotaxin Inhibitor, and Lung Function in Idiopathic Pulmonary Fibrosis: The ISABELA 1 and 2 Randomized Clinical Trials.
JAMA
; 329(18): 1567-1578, 2023 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37159034
6.
Efficacy and safety of inhaled nitrite in addition to sildenafil in thalassemia patients with pulmonary hypertension: A 12-week randomized, double-blind placebo-controlled clinical trial.
Nitric Oxide
; 120: 38-43, 2022 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35026396
7.
Phase 1 Single Ascending and Multiple Ascending Dose Studies of Phosphodiesterase-9 Inhibitor E2027: Confirmation of Target Engagement and Selection of Phase 2 Dose in Dementia With Lewy Bodies Trial.
Alzheimer Dis Assoc Disord
; 36(3): 200-207, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35700341
8.
Combined ligand-based and structure-based design of PDE 9A inhibitors against Alzheimer's disease.
Mol Divers
; 26(5): 2877-2892, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35932437
9.
Current trends in erectile rehabilitation after radical prostatectomy: Results from a worldwide survey.
Andrologia
; 54(9): e14506, 2022 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-35780809
10.
Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis.
N Engl J Med
; 379(9): 846-855, 2018 08 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-30157388
11.
Hypercontractile Esophagus From Pathophysiology to Management: Proceedings of the Pisa Symposium.
Am J Gastroenterol
; 116(2): 263-273, 2021 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33273259
12.
Ibudilast attenuates alcohol cue-elicited frontostriatal functional connectivity in alcohol use disorder.
Alcohol Clin Exp Res
; 45(10): 2017-2028, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34585396
13.
Pentoxifylline treatment alleviates kidney ischemia/reperfusion injury: Novel involvement of galectin-3 and ASK-1/JNK & ERK1/2/NF-κB/HMGB-1 trajectories.
J Pharmacol Sci
; 146(3): 136-148, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34030796
14.
Ibudilast suppresses oxaliplatin-induced mechanical allodynia and neurodegeneration in rats.
J Pharmacol Sci
; 147(1): 114-117, 2021 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-34294361
15.
Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease.
Nature
; 519(7544): 472-6, 2015 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-25799991
16.
A randomized double-blinded placebo-controlled clinical trial on protective effects of pentoxifylline on gentamicin nephrotoxicity in infectious patients.
Clin Exp Nephrol
; 25(8): 844-853, 2021 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-33792832
17.
Phosphodiesterase Inhibitors in Acute Lung Injury: What Are the Perspectives?
Int J Mol Sci
; 22(4)2021 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33669167
18.
Increased Autotaxin Levels in Severe COVID-19, Correlating with IL-6 Levels, Endothelial Dysfunction Biomarkers, and Impaired Functions of Dendritic Cells.
Int J Mol Sci
; 22(18)2021 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-34576169
19.
Design, Synthesis, and Evaluation of Dihydropyranopyrazole Derivatives as Novel PDE2 Inhibitors for the Treatment of Alzheimer's Disease.
Molecules
; 26(10)2021 May 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34069639
20.
Pentoxifylline: A Drug with Antiviral and Anti-Inflammatory Effects to Be Considered in the Treatment of Coronavirus Disease 2019.
Med Princ Pract
; 30(1): 98-100, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33049737